The synthesis and the anticonvulsant activity screening of new 5-substituted 2-imino-4-thiazolidinone derivatives

Aim. To synthesize 5-ene-4-thiazolidinones containing heterocyclic rings in the molecule as potential anticonvulsants, and screen their anticonvulsant activity on a model of pentylenetetrazole (PTZ) seizures. Results and discussion. A straightforward and convenient synthesis of novel 5-ene-derivati...

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Principais autores:	Ivan A. Sydorenko, Marija V. Mishchenko, Serhii Yu. Shtrygol’, Andriy V. Lozynskyy, Ihor I. Soronovych, Serhii M. Holota, Roman B. Lesyk
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National University of Pharmacy (Kharkiv) 2022-05-01
Colecção:	Журнал органічної та фармацевтичної хімії
Assuntos:	4-thiazolidinones dimroth reaction knoevenagel reaction antiepileptic drugs epilepsy anticonvulsant activity
Acesso em linha:	http://ophcj.nuph.edu.ua/article/view/248784
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