Attrition of methylnaltrexone treatment-emergent adverse events in patients with chronic noncancer pain and opioid-induced constipation: a post hoc pooled analysis of two clinical trials [version 2; peer review: 2 approved]
Background: Opioids prescribed for the management of chronic noncancer pain are associated with nausea, vomiting, and constipation. Methylnaltrexone, a peripherally acting µ-opioid receptor antagonist, has demonstrated robust efficacy and was well-tolerated in treating opioid-induced constipation wi...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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F1000 Research Ltd
2023-07-01
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| coleção: | F1000Research |
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| Acesso em linha: | https://f1000research.com/articles/10-891/v2 |
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