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The probability of chromatin to be at the nuclear lamina has no systematic effect on its transcription level in fruit flies

Abstract Background Multiple studies have demonstrated a negative correlation between gene expression and positioning of genes at the nuclear envelope (NE) lined by nuclear lamina, but the exact relationship remains unclear, especially in light of the highly stochastic, transient nature of the gene...

Celý popis

Uloženo v:
Hlavní autoři: Alexander Y. Afanasyev, Yoonjin Kim, Igor S. Tolokh, Igor V. Sharakhov, Alexey V. Onufriev
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2024-05-01
Edice:Epigenetics & Chromatin
Témata:
Drosophila
Transcription levels
TAD
RPKM
Chromosome model
Nuclear envelope
On-line přístup:https://doi.org/10.1186/s13072-024-00528-8
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