The probability of chromatin to be at the nuclear lamina has no systematic effect on its transcription level in fruit flies

Abstract Background Multiple studies have demonstrated a negative correlation between gene expression and positioning of genes at the nuclear envelope (NE) lined by nuclear lamina, but the exact relationship remains unclear, especially in light of the highly stochastic, transient nature of the gene...

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主要な著者:	Alexander Y. Afanasyev, Yoonjin Kim, Igor S. Tolokh, Igor V. Sharakhov, Alexey V. Onufriev
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2024-05-01
シリーズ:	Epigenetics & Chromatin
主題:	Drosophila Transcription levels TAD RPKM Chromosome model Nuclear envelope
オンライン･アクセス:	https://doi.org/10.1186/s13072-024-00528-8
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