ALS and Parkinson's disease genes CHCHD10 and CHCHD2 modify synaptic transcriptomes in human iPSC-derived motor neurons

Mitochondrial intermembrane space proteins CHCHD2 and CHCHD10 have roles in motor neuron diseases such as amyotrophic lateral sclerosis, spinal muscular atrophy and axonal neuropathy and in Parkinson's disease. They form a complex of unknown function. Here we address the importance of these two prot...

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Үндсэн зохиолчид:	Sandra Harjuhaahto, Tiina S. Rasila, Svetlana M. Molchanova, Rosa Woldegebriel, Jouni Kvist, Svetlana Konovalova, Markus T. Sainio, Jana Pennonen, Rubén Torregrosa-Muñumer, Hazem Ibrahim, Timo Otonkoski, Tomi Taira, Emil Ylikallio, Henna Tyynismaa
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2020-07-01
Цуврал:	Neurobiology of Disease
Нөхцлүүд:	CHCHD2 CHCHD10 Induced pluripotent stem cell Motor neuron differentiation CMT2 SMAJ
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S0969996120302151
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!