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Novel Bifunctional Acylase from <i>Actinoplanes utahensis</i>: A Versatile Enzyme to Synthesize Antimicrobial Compounds and Use in Quorum Quenching Processes

Many intercellular communication processes, known as quorum sensing (QS), are regulated by the autoinducers <i>N</i>-acyl-<span style="font-variant: small-caps;">l</span>-homoserine lactones (AHLs) in Gram-negative bacteria. The inactivation of these QS processes using different quorum quenching (QQ...

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Gardado en:
Principais autores: Lara Serrano-Aguirre, Rodrigo Velasco-Bucheli, Begoña García-Álvarez, Ana Saborido, Miguel Arroyo, Isabel de la Mata
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2021-07-01
Series:Antibiotics
Assuntos:
<i>N</i>-acyl-homoserine lactone
<i>N</i>-acyl-homoserine lactone acylase
penicillin acylase
Ntn-hydrolase
quorum sensing
quorum quenching
Acceso en liña:https://www.mdpi.com/2079-6382/10/8/922
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