SecM-stalled ribosomes adopt an altered geometry at the peptidyl transferase center.
As nascent polypeptide chains are synthesized, they pass through a tunnel in the large ribosomal subunit. Interaction between specific nascent chains and the ribosomal tunnel is used to induce translational stalling for the regulation of gene expression. One well-characterized example is the Escheri...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science (PLoS)
2011-01-01
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| Серии: | PLoS Biology |
| Online-ссылка: | http://europepmc.org/articles/PMC3022528?pdf=render |
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