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Identification of natural inhibitors of Entamoeba histolytica cysteine synthase from microbial secondary metabolites

Amebiasis is a common worldwide diarrheal disease, caused by the protozoan parasite, Entamoeba histolytica. Metronidazole has been a drug of choice against amebiasis for decades despite its known side effects and low efficacy against asymptomatic cyst carriers. E. histolytica is also capable of surv...

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Tallennettuna:
Päätekijät: Mihoko eMori, Ghulam eJeelani, Yui eMasuda, Kazunari eSakai, Kumiko eNakada-Tsukui, Danang eWaluyo, Tarwadi e_, Yoshio eWatanabe, Kenichi eNonaka, Atsuko eMatsumoto, Satoshi eŌmura, Tomoyoshi eNozaki, Kazuro eShiomi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2015-09-01
Sarja:Frontiers in Microbiology
Aiheet:
Amebiasis
Cysteine Synthase
Entamoeba histolytica
secondary metabolites
compound library screening
Linkit:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00962/full
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