Identification of natural inhibitors of Entamoeba histolytica cysteine synthase from microbial secondary metabolites

Amebiasis is a common worldwide diarrheal disease, caused by the protozoan parasite, Entamoeba histolytica. Metronidazole has been a drug of choice against amebiasis for decades despite its known side effects and low efficacy against asymptomatic cyst carriers. E. histolytica is also capable of surv...

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Autors principals:	Mihoko eMori, Ghulam eJeelani, Yui eMasuda, Kazunari eSakai, Kumiko eNakada-Tsukui, Danang eWaluyo, Tarwadi e_, Yoshio eWatanabe, Kenichi eNonaka, Atsuko eMatsumoto, Satoshi eŌmura, Tomoyoshi eNozaki, Kazuro eShiomi
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2015-09-01
Col·lecció:	Frontiers in Microbiology
Matèries:	Amebiasis Cysteine Synthase Entamoeba histolytica secondary metabolites compound library screening
Accés en línia:	http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00962/full
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