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Immunoregulatory properties of cell free DNA

Abstract Cell free DNA (cfDNA) is detectable at low concentrations in the plasma of healthy subjects and at high concentrations in disorders characterized by a high rate of necrotic events, such as tumors and vasculitis, leading to the release of necrotic DNA into the surrounding tissue and the bloo...

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Autors principals: Francesca Ferrera, Tiziana Altosole, Samuele Tardito, Giuseppina Astone, Cinzia Bernardi, Alessia Parodi, Chiara Marini, Giuseppina Conteduca, Elena Cichero, Annalisa Salis, Leonardo Arpesella, Laura Camporesi, Andrea Lagazio, Valentina Rigo, Andrea Pigozzo, Gianluca Damonte, Paola Fossa, Daniela Fenoglio, Raffaele De Palma, Giorgio Inghirami, Gilberto Filaci
Format: Artigo
Idioma:Inglês
Publicat: Springer 2025-08-01
Col·lecció:Cellular and Molecular Life Sciences
Matèries:
Immune-modulations
Cell free DNAs
Autoimmune diseases
Tumors
Accés en línia:https://doi.org/10.1007/s00018-025-05862-y
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