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Immunoregulatory properties of cell free DNA

Abstract Cell free DNA (cfDNA) is detectable at low concentrations in the plasma of healthy subjects and at high concentrations in disorders characterized by a high rate of necrotic events, such as tumors and vasculitis, leading to the release of necrotic DNA into the surrounding tissue and the bloo...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Francesca Ferrera, Tiziana Altosole, Samuele Tardito, Giuseppina Astone, Cinzia Bernardi, Alessia Parodi, Chiara Marini, Giuseppina Conteduca, Elena Cichero, Annalisa Salis, Leonardo Arpesella, Laura Camporesi, Andrea Lagazio, Valentina Rigo, Andrea Pigozzo, Gianluca Damonte, Paola Fossa, Daniela Fenoglio, Raffaele De Palma, Giorgio Inghirami, Gilberto Filaci
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer 2025-08-01
Schriftenreihe:Cellular and Molecular Life Sciences
Schlagworte:
Immune-modulations
Cell free DNAs
Autoimmune diseases
Tumors
Online-Zugang:https://doi.org/10.1007/s00018-025-05862-y
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