Acetyl-carnitine improves hyperactivity and learning deficits in KAT6A haploinsufficient mice

In this study, the authors show that treatment with acetyl-carnitine can ameliorate learning and memory defects and hyperactivity in a mouse model of the cognitive disorder, Arboleda–Tham syndrome. Pathogenic variants in one allele of the KAT6A gene encoding the histone acetyltransferase KAT6A (MOZ,...

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Principais autores:	Samantha Eccles, Hannah K Vanyai, Maria I Bergamasco, Shezlie Malelang, Havva Pehlivanoglu, Alexandra L Garnham, Nishika Ranathunga, Marnie E Blewitt, Adam P Vogel, Gordon K Smyth, Anthony J Hannan, Tim Thomas, Anne K Voss
Format:	Artigo
Jezik:	Inglês
Izdano:	Life Science Alliance LLC 2026-05-01
Serija:	Life Science Alliance
Online dostop:	https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202503549
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