KAT6B overexpression rescues embryonic lethality in homozygous null KAT6A mice restoring vitality and normal lifespan

Abstract Closely related genes typically display common essential functions but also functional diversification, ensuring retention of both genes throughout evolution. The histone lysine acetyltransferases KAT6A (MOZ) and KAT6B (QKF/MORF), sharing identical protein domain structure, are mutually exc...

Cijeli opis

Bibliografski detalji

Glavni autori:	Maria. I. Bergamasco, Yuqing Yang, Alexandra L. Garnham, Bilal N. Sheikh, Gordon K. Smyth, Anne. K. Voss, Tim Thomas
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Portfolio 2025-02-01
Serija:	Nature Communications
Online pristup:	https://doi.org/10.1038/s41467-025-57155-4
Oznake:	Dodaj oznaku Bez oznaka, Budi prvi tko označuje ovaj zapis!