KAT6B overexpression rescues embryonic lethality in homozygous null KAT6A mice restoring vitality and normal lifespan

Abstract Closely related genes typically display common essential functions but also functional diversification, ensuring retention of both genes throughout evolution. The histone lysine acetyltransferases KAT6A (MOZ) and KAT6B (QKF/MORF), sharing identical protein domain structure, are mutually exc...

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Autores principales:	Maria. I. Bergamasco, Yuqing Yang, Alexandra L. Garnham, Bilal N. Sheikh, Gordon K. Smyth, Anne. K. Voss, Tim Thomas
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Portfolio 2025-02-01
Colección:	Nature Communications
Acceso en línea:	https://doi.org/10.1038/s41467-025-57155-4
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