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Reduced tissue osmolarity increases TRPV4 expression and pro-inflammatory cytokines in intervertebral disc cells

The mechanical behaviour and cellular metabolism of intervertebral discs (IVDs) and articular cartilage are strongly influenced by their proteoglycan content and associated osmotic properties. This osmotic environment is a biophysical signal that changes with disease and may contribute to the elevat...

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書誌詳細
主要な著者: BA Walter, D Purmessur, A Moon, J Occhiogrosso, DM Laudier, AC Hecht, JC Iatridis
フォーマット: Artigo
言語:Inglês
出版事項: Forum Multimedia Publishing LLC 2016-07-01
シリーズ:European Cells & Materials
主題:
オンライン・アクセス:http://www.ecmjournal.org/papers/vol032/pdf/v032a08.pdf
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