Senotherapeutic drugs for human intervertebral disc degeneration and low back pain
Cellular senescence is a contributor to intervertebral disc (IVD) degeneration and low back pain. Here, we found that RG-7112, a potent mouse double-minute two protein inhibitor, selectively kills senescent IVD cells through apoptosis. Gene expression pathway analysis was used to compare the functio...
Sábháilte in:
| Príomhchruthaitheoirí: | , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe / Cruthaithe: |
eLife Sciences Publications Ltd
2020-08-01
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| Sraith: | eLife |
| Ábhair: | |
| Rochtain ar líne: | https://elifesciences.org/articles/54693 |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
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