Lipotoxic Impairment of Mitochondrial Function in β-Cells: A Review
Lipotoxicity is a major contributor to type 2 diabetes mainly promoting mitochondrial dysfunction. Lipotoxic stress is mediated by elevated levels of free fatty acids through various mechanisms and pathways. Impaired peroxisome proliferator-activated receptor (PPAR) signaling, enhanced oxidative str...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI AG
2021-02-01
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| Collection: | Antioxidants |
| Sujets: | |
| Accès en ligne: | https://www.mdpi.com/2076-3921/10/2/293 |
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