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Lipotoxic Impairment of Mitochondrial Function in β-Cells: A Review

Lipotoxicity is a major contributor to type 2 diabetes mainly promoting mitochondrial dysfunction. Lipotoxic stress is mediated by elevated levels of free fatty acids through various mechanisms and pathways. Impaired peroxisome proliferator-activated receptor (PPAR) signaling, enhanced oxidative str...

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Détails bibliographiques
Auteurs principaux: Axel Römer, Thomas Linn, Sebastian F. Petry
Format: Artigo
Langue:Inglês
Publié: MDPI AG 2021-02-01
Collection:Antioxidants
Sujets:
Accès en ligne:https://www.mdpi.com/2076-3921/10/2/293
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