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Consecutive low-frequency shifts in A/T content denote nucleosome positions across microeukaryotes

Summary: Nucleosomes are the basic repeating unit, each spanning ≈150bp, that structures DNA in the nucleus and their positions have major consequences on gene activity. Here, through analyzing DNA signatures across 1117 microeukaryote genomes, we discovered ≈150bp shifts in A/T content associated w...

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Principais autores: Stephen J. Mondo, Guifen He, Aditi Sharma, Doina Ciobanu, Robert Riley, William B. Andreopoulos, Anna Lipzen, Alan Kuo, Kurt LaButti, Jasmyn Pangilinan, Asaf Salamov, Hugh Salamon, Lili Shu, John Gladden, Jon Magnuson, M. Catherine Aime, Ronan O’Malley, Igor V. Grigoriev
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2025-05-01
coleção:iScience
Assuntos:
Genomics
Chromosome organization
Molecular interaction
Model organism
Artificial intelligence
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2589004225007333
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