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Genomic and proteomic biases inform metabolic engineering strategies for anaerobic fungi

Anaerobic fungi (Neocallimastigomycota) are emerging non-model hosts for biotechnology due to their wealth of biomass-degrading enzymes, yet tools to engineer these fungi have not yet been established. Here, we show that the anaerobic gut fungi have the most GC depleted genomes among 443 sequenced o...

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Principais autores: St. Elmo Wilken, Susanna Seppälä, Thomas S. Lankiewicz, Mohan Saxena, John K. Henske, Asaf A. Salamov, Igor V. Grigoriev, Michelle A. O’Malley
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020-06-01
Serier:Metabolic Engineering Communications
Fag:
Codon optimization
Amino acid distribution
Anaerobe
Genome sequencing
Fungi
Neocallimastigomycota
Online adgang:http://www.sciencedirect.com/science/article/pii/S2214030119300276
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