A novel synthetic oleanane triterpenoid, 2‐cyano‐3,12‐dioxoolean‐1,9‐dien‐28‐oic acid, regulates mechanical allodynia by rescuing neuronal cell death and glial cell activation in the spinal cord of resiniferatoxin‐treated rats

Abstract Background Treating postherpetic neuralgia (PHN), which is characterized with a long‐lasting lancinating mechanical allodynia or hyperalgesia, is a big challenge as it is hard to achieve complete resolution. A synthetic triterpenoid, CDDO (2‐cyano‐3,12‐dioxoolean‐1,9‐dien‐28‐oic acid) can e...

Volledige beschrijving

Bibliografische gegevens

Hoofdauteurs:	Ying‐Yi Lu, Chia‐Yang Lin, Hung‐Pei Tsai, Chih‐Lung Lin, Chieh‐Hsin Wu
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Wiley 2024-02-01
Reeks:	Brain and Behavior
Onderwerpen:	2‐cyano‐3,12‐dioxoolean‐1,9‐dien‐28‐oic acid mechanical allodynia resiniferatoxin triterpenoid
Online toegang:	https://doi.org/10.1002/brb3.3398
Tags:	Voeg label toe Geen labels, Wees de eerste die dit record labelt!