Cathepsin C from extracellular histone-induced M1 alveolar macrophages promotes NETosis during lung ischemia-reperfusion injury

Primary graft dysfunction (PGD) is a severe form of acute lung injury resulting from lung ischemia/reperfusion injury (I/R) in lung transplantation (LTx), associated with elevated post-transplant morbidity and mortality rates. Neutrophils infiltrating during reperfusion are identified as pivotal con...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Jing Yu, Yu Fu, Jiameng Gao, Qingqing Zhang, Nan Zhang, Zhiyuan Zhang, Xuemei Jiang, Chang Chen, Zongmei Wen
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2024-08-01
Цуврал:	Redox Biology
Нөхцлүүд:	Lung ischemia-reperfusion injury NETosis Alveolar macrophages Cathepsin C NADPH oxidase
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S221323172400209X
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!