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Cathepsin C from extracellular histone-induced M1 alveolar macrophages promotes NETosis during lung ischemia-reperfusion injury

Primary graft dysfunction (PGD) is a severe form of acute lung injury resulting from lung ischemia/reperfusion injury (I/R) in lung transplantation (LTx), associated with elevated post-transplant morbidity and mortality rates. Neutrophils infiltrating during reperfusion are identified as pivotal con...

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Kaydedildi:
Asıl Yazarlar: Jing Yu, Yu Fu, Jiameng Gao, Qingqing Zhang, Nan Zhang, Zhiyuan Zhang, Xuemei Jiang, Chang Chen, Zongmei Wen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2024-08-01
Seri Bilgileri:Redox Biology
Konular:
Lung ischemia-reperfusion injury
NETosis
Alveolar macrophages
Cathepsin C
NADPH oxidase
Online Erişim:http://www.sciencedirect.com/science/article/pii/S221323172400209X
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