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Adenosine A1 receptors of the medullary solitary tract arbitrate the nicotine counteraction of neuroinflammation and cardiovascular dysfunction in septic rats

Abstract The cholinergic pathway plays a crucial role in improving inflammatory end-organ damage. Given the interplay between cholinergic and adenosinergic neurotransmission, we tested the hypothesis that central adenosine A1 receptors (A1ARs) modulate the nicotine counteraction of cardiovascular an...

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Autors principals: Amany E. El-Naggar, Mai M. Helmy, Sahar M. El-Gowilly, Mahmoud M. El-Mas
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2023-10-01
Col·lecció:Scientific Reports
Accés en línia:https://doi.org/10.1038/s41598-023-44601-w
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