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Characterization of Sigma-2 Receptor—Specific Binding Sites Using [<sup>3</sup>H]DTG and [<sup>125</sup>I]RHM-4

The sigma-2 receptor/transmembrane protein 97 (σ2R/TMRM97) is a promising biomarker of tumor proliferation and a target for cancer therapy. [<sup>3</sup>H]DTG has been used to evaluate σ2R/TMEM97 binding affinity in compound development studies. However, [<sup>3</sup>H]DTG has equal and moderate bin...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Chi-Chang Weng, Aladdin Riad, Brian P. Lieberman, Kuiying Xu, Xin Peng, John L. Mikitsh, Robert H. Mach
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2022-12-01
Rangatū:Pharmaceuticals
Ngā marau:
Urunga tuihono:https://www.mdpi.com/1424-8247/15/12/1564
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