Characterization of Sigma-2 Receptor—Specific Binding Sites Using [³H]DTG and [¹²⁵I]RHM-4

The sigma-2 receptor/transmembrane protein 97 (σ2R/TMRM97) is a promising biomarker of tumor proliferation and a target for cancer therapy. [³H]DTG has been used to evaluate σ2R/TMEM97 binding affinity in compound development studies. However, [³H]DTG has equal and moderate bin...

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Bibliografski detalji

Glavni autori:	Chi-Chang Weng, Aladdin Riad, Brian P. Lieberman, Kuiying Xu, Xin Peng, John L. Mikitsh, Robert H. Mach
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2022-12-01
Serija:	Pharmaceuticals
Teme:	Sigma-2 receptor [<sup>3</sup>H]DTG [<sup>125</sup>I]RHM-4 (+)-pentazocine σ1R masking procedure
Online pristup:	https://www.mdpi.com/1424-8247/15/12/1564
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