Local heterogeneity of normal lung parenchyma and small airways disease are associated with COPD severity and progression

Abstract Background Small airways disease (SAD) is a major cause of airflow obstruction in COPD patients and has been identified as a precursor to emphysema. Although the amount of SAD in the lungs can be quantified using our Parametric Response Mapping (PRM) approach, the full breadth of this reado...

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Bibliografiska uppgifter

Huvudupphov:	Alexander J. Bell, Ravi Pal, Wassim W. Labaki, Benjamin A. Hoff, Jennifer M. Wang, Susan Murray, Ella A. Kazerooni, Stefanie Galban, David A. Lynch, Stephen M. Humphries, Fernando J. Martinez, Charles R. Hatt, MeiLan K. Han, Sundaresh Ram, Craig J. Galban
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	BMC 2024-02-01
Serie:	Respiratory Research
Ämnen:	Chronic obstructive pulmonary disease Small airways disease Parametric response mapping Computed tomography of the chest Machine learning Emphysema
Länkar:	https://doi.org/10.1186/s12931-024-02729-x
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