Integrated single-cell and transcriptomic profiling identifies machine-learning–based pyroptosis biomarkers in IBD

BackgroundPyroptosis, an inflammatory form of programmed cell death, contributes to intestinal inflammation in inflammatory bowel disease (IBD), but the key cell types and regulatory genes remain unclear.MethodsWe analyzed single-cell RNA-seq data from intestinal mucosa to assess pyroptosis-related...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Yao Lu, Yahui Lin, Yuansen Li, Huan Sai, Cheng Chen, Jinjiao Li
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2026-02-01
Serija:	Frontiers in Immunology
Teme:	inflammatory bowel disease machine learning pyroptosis single-cell RNA sequencing transcriptomic integration
Online dostop:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1761476/full
Oznake:	Označite Brez oznak, prvi označite!