In vivo imaging of injured cortical axons reveals a rapid onset form of Wallerian degeneration

Abstract Background Despite the widespread occurrence of axon and synaptic loss in the injured and diseased nervous system, the cellular and molecular mechanisms of these key degenerative processes remain incompletely understood. Wallerian degeneration (WD) is a tightly regulated form of axon loss a...

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Principais autores:	Alison Jane Canty, Johanna Sara Jackson, Lieven Huang, Antonio Trabalza, Cher Bass, Graham Little, Maria Tortora, Shabana Khan, Vincenzo De Paola
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2020-11-01
coleção:	BMC Biology
Assuntos:	Wallerian degeneration Brain Cortex Cortical axons In vivo imaging Synapses
Acesso em linha:	http://link.springer.com/article/10.1186/s12915-020-00869-2
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