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Calpains mediate axonal cytoskeleton disintegration during Wallerian degeneration

In both the central nervous system (CNS) and peripheral nervous system (PNS), transected axons undergo Wallerian degeneration. Even though Augustus Waller first described this process after transection of axons in 1850, the molecular mechanisms may be shared, at least in part, by many human diseases...

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Príomhchruthaitheoirí: Marek Ma, Toby A. Ferguson, Kathleen M. Schoch, Jian Li, Yaping Qian, Frances S. Shofer, Kathryn E. Saatman, Robert W. Neumar
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Elsevier 2013-08-01
Sraith:Neurobiology of Disease
Ábhair:
Rochtain ar líne:http://www.sciencedirect.com/science/article/pii/S0969996113000971
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