NPC 15669 blocks neutrophil CD18 increase and lung injury during cardiopulmonary bypass in pigs

During cardiopulmonary bypass (CPB), neutrophils become activated due to contact with extracorporeal surfaces and binding of complement fragments C3a and C5a, leading to extravasation and subsequent tissue damage. In this study, the effects of the leumedin NPC 15669 (N [9H - (2,7 dimethylfluorenyl -...

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Detalles Bibliográficos

Principais autores:	J. M. Bator, A. M. Gillinov, K. J. Zehr, J. M. Redmond, I. C. Wilson, A. Herskowitz, J. R. Connor, R. M. Burch, D. E. Cameron
Formato:	Artigo
Idioma:	Inglês
Publicado:	Wiley 1993-01-01
Series:	Mediators of Inflammation
Acceso en liña:	http://dx.doi.org/10.1155/S0962935193000201
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