NPC 15669 blocks neutrophil CD18 increase and lung injury during cardiopulmonary bypass in pigs
During cardiopulmonary bypass (CPB), neutrophils become activated due to contact with extracorporeal surfaces and binding of complement fragments C3a and C5a, leading to extravasation and subsequent tissue damage. In this study, the effects of the leumedin NPC 15669 (N [9H - (2,7 dimethylfluorenyl -...
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| Principais autores: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley
1993-01-01
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| Colecção: | Mediators of Inflammation |
| Acesso em linha: | http://dx.doi.org/10.1155/S0962935193000201 |
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