Cyclophilin B deficiency enhances myocardial energy synthesis and protects against heart failure in preclinical models
Abstract Background Heart failure (HF) represents the end stage of cardiovascular diseases with high mortality and limited treatment options. Cyclophilin B (CypB), known mainly as an endoplasmic reticulum chaperone, has been implicated in cardiovascular diseases. But the role of CypB in HF remains u...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BMC
2025-12-01
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| Series: | BMC Medicine |
| Assuntos: | |
| Acceso en liña: | https://doi.org/10.1186/s12916-025-04563-4 |
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