Aberrant overexpression of HOTAIR inhibits abdominal adipogenesis through remodelling of genome-wide DNA methylation and transcription

Objective: Abdominal adiposity is strongly associated with diabetic and cardiovascular comorbidities. The long noncoding RNA HOTAIR (HOX Transcript Antisense Intergenic RNA) is an important epigenetic regulator with fat depot-specific expression. Its functional roles and epigenetic regulation in abd...

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Үндсэн зохиолчид:	Feng-Chih Kuo, Yu-Chun Huang, Ming-Ren Yen, Chien-Hsing Lee, Kuo-Feng Hsu, Hsiang-Yu Yang, Li-Wei Wu, Chieh-Hua Lu, Yu-Juei Hsu, Pao-Yang Chen
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2022-06-01
Цуврал:	Molecular Metabolism
Нөхцлүүд:	lncRNA HOTAIR Subcutaneous adipose tissue Visceral adipose tissue Abdominal adipogenesis Epigenetic regulation
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S2212877822000424
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!