Analysis of Anti-Influenza Virus Neuraminidase Antibodies in Children, Adults, and the Elderly by ELISA and Enzyme Inhibition: Evidence for Original Antigenic Sin

ABSTRACT Antibody responses to influenza virus hemagglutinin provide protection against infection and are well studied. Less is known about the human antibody responses to the second surface glycoprotein, neuraminidase. Here, we assessed human antibody reactivity to a panel of N1, N2, and influenza...

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Библиографические подробности

Главные авторы:	Madhusudan Rajendran, Raffael Nachbagauer, Megan E. Ermler, Paul Bunduc, Fatima Amanat, Ruvim Izikson, Manon Cox, Peter Palese, Maryna Eichelberger, Florian Krammer
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology 2017-05-01
Серии:	mBio
Предметы:	influenza influenza virus neuraminidase neuraminidase inhibition
Online-ссылка:	https://journals.asm.org/doi/10.1128/mBio.02281-16
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