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Systemic infection and microglia activation: a prospective postmortem study in sepsis patients

Abstract Background Systemic infection is associated with long-term cognitive deficits and functional decline. In this study we hypothesized that severe systemic inflammation leads to a neuroinflammatory response that is characterized by microglial activation, and that these effects might be more pr...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: D. Westhoff, J. Y. Engelen-Lee, I. C. M. Hoogland, E. M. A. Aronica, D. J. van Westerloo, D. van de Beek, W. A. van Gool
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2019-07-01
Schriftenreihe:Immunity & Ageing
Schlagworte:
Sepsis
Delirium
Microglia
Neuroinflammation
Sepsis associated encephalopathy
Online-Zugang:http://link.springer.com/article/10.1186/s12979-019-0158-7
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