Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

ABSTRACT Aristolochic acids (AAs) are natural compounds found in Aristolochiaceae plants, to which humans are frequently exposed through environmental and medicinal sources. AAs are highly nephrotoxic and carcinogenic, mediated by oxidative stress and bioactivation‐induced DNA damage and mutagenicit...

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Váldodahkkit:	Yang Luan, Yubo Zhang, Jingjing Li, Jianqing Zhu, Yuyang Lei, Yushi Hu, Zhenqiang Xin, Tianpei Xie, Jiang Zheng, Yuanyuan Lin, Jingjing Shen, Yiyi Cao, Xinyue You, Jing Xi, Jiaying Wu, Weiying Liu, Xinyu Zhang, Yuanting Zheng, David J. Lohman, Leming Shi, Wei Zhang
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Wiley 2026-04-01
Ráidu:	Advanced Science
Fáttát:	antioxidant Aristolochiaceae butterflies chemical defense DNA repair multiomics
Liŋkkat:	https://doi.org/10.1002/advs.202518072
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