Enhancing mRNA translation efficiency with discriminative and generative artificial intelligence by optimizing 5′ UTR sequences
Summary: The mRNA-based therapeutics, notably mRNA vaccines, represent a new era of powerful tools to combat various diseases. However, the relatively low translation efficiency of exogenous mRNA often limits its wide application. Here, we propose a computational framework called UTailoR (UTR tailor...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Elsevier
2025-10-01
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| Seri Bilgileri: | iScience |
| Konular: | |
| Online Erişim: | http://www.sciencedirect.com/science/article/pii/S258900422501805X |
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