Enhancing mRNA translation efficiency with discriminative and generative artificial intelligence by optimizing 5′ UTR sequences
Summary: The mRNA-based therapeutics, notably mRNA vaccines, represent a new era of powerful tools to combat various diseases. However, the relatively low translation efficiency of exogenous mRNA often limits its wide application. Here, we propose a computational framework called UTailoR (UTR tailor...
Guardat en:
| Autors principals: | , , , |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2025-10-01
|
| Col·lecció: | iScience |
| Matèries: | |
| Accés en línia: | http://www.sciencedirect.com/science/article/pii/S258900422501805X |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|