Crystal structure of a PP2A B56-BubR1 complex and its implications for PP2A substrate recruitment and localization

ABSTRACT Protein phosphatase 2A (PP2A) accounts for the majority of total Ser/Thr phosphatase activities in most cell types and regulates many biological processes. PP2A holoenzymes contain a scaffold A subunit, a catalytic C subunit, and one of the regulatory/targeting B subunits. How the B subunit...

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主要な著者:	Jiao Wang, Zhizhi Wang, Tingting Yu, Huan Yang, David M. Virshup, Geert J. P. L. Kops, Sang Hyun Lee, Weihong Zhou, Xin Li, Wenqing Xu, Zihe Rao
フォーマット:	Artigo
言語:	Inglês
出版事項:	Oxford University Press 2016-06-01
シリーズ:	Protein & Cell
主題:	PP2A BubR1 kinetochore cellular targeting substrate recruitment
オンライン･アクセス:	http://link.springer.com/article/10.1007/s13238-016-0283-4
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