BUBR1 Pseudokinase Domain Promotes Kinetochore PP2A-B56 Recruitment, Spindle Checkpoint Silencing, and Chromosome Alignment

Summary: The balance of phospho-signaling at the outer kinetochore is critical for forming accurate attachments between kinetochores and the mitotic spindle and timely exit from mitosis. A major player in determining this balance is the PP2A-B56 phosphatase, which is recruited to the kinase attachme...

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Hlavní autoři:	Luciano Gama Braga, Angel F. Cisneros, Michelle M. Mathieu, Maxime Clerc, Pauline Garcia, Baptiste Lottin, Chantal Garand, Philippe Thebault, Christian R. Landry, Sabine Elowe
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2020-11-01
Edice:	Cell Reports
Témata:	BUBR1 pseudokinase PP2A B56 Kinetochore Spindle checkpoint
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2211124720313863
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