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BUBR1 Pseudokinase Domain Promotes Kinetochore PP2A-B56 Recruitment, Spindle Checkpoint Silencing, and Chromosome Alignment

Summary: The balance of phospho-signaling at the outer kinetochore is critical for forming accurate attachments between kinetochores and the mitotic spindle and timely exit from mitosis. A major player in determining this balance is the PP2A-B56 phosphatase, which is recruited to the kinase attachme...

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Detalhes bibliográficos
Principais autores: Luciano Gama Braga, Angel F. Cisneros, Michelle M. Mathieu, Maxime Clerc, Pauline Garcia, Baptiste Lottin, Chantal Garand, Philippe Thebault, Christian R. Landry, Sabine Elowe
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020-11-01
Colecção:Cell Reports
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Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2211124720313863
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