The efficiency of murine MLL-ENL–driven leukemia initiation changes with age and peaks during neonatal development

Abstract: MLL rearrangements are translocation mutations that cause both acute lymphoblastic leukemia and acute myeloid leukemia (AML). These translocations can occur as sole clonal driver mutations in infant leukemias, suggesting that fetal or neonatal hematopoietic progenitors may be exquisitely s...

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מידע ביבליוגרפי

Principais autores:	Theresa Okeyo-Owuor, Yanan Li, Riddhi M. Patel, Wei Yang, Emily B. Casey, Andrew S. Cluster, Shaina N. Porter, David Bryder, Jeffrey A. Magee
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Elsevier 2019-08-01
סדרה:	Blood Advances
גישה מקוונת:	http://www.sciencedirect.com/science/article/pii/S2473952920306352
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