The efficiency of murine MLL-ENL–driven leukemia initiation changes with age and peaks during neonatal development

Abstract: MLL rearrangements are translocation mutations that cause both acute lymphoblastic leukemia and acute myeloid leukemia (AML). These translocations can occur as sole clonal driver mutations in infant leukemias, suggesting that fetal or neonatal hematopoietic progenitors may be exquisitely s...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Theresa Okeyo-Owuor, Yanan Li, Riddhi M. Patel, Wei Yang, Emily B. Casey, Andrew S. Cluster, Shaina N. Porter, David Bryder, Jeffrey A. Magee
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Elsevier 2019-08-01
Sarja:	Blood Advances
Linkit:	http://www.sciencedirect.com/science/article/pii/S2473952920306352
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!