Trans‐generational epigenetic regulation associated with the amelioration of Duchenne Muscular Dystrophy

Abstract Exon skipping is an effective strategy for the treatment of many Duchenne Muscular Dystrophy (DMD) mutations. Natural exon skipping observed in several DMD cases can help in identifying novel therapeutic tools. Here, we show a DMD study case where the lack of a splicing factor (Celf2a), whi...

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Bibliografiska uppgifter

Huvudupphov:	Julie Martone, Michela Lisi, Francesco Castagnetti, Alessandro Rosa, Valerio Di Carlo, Enrique Blanco, Adriano Setti, Davide Mariani, Alessio Colantoni, Tiziana Santini, Lucia Perone, Luciano Di Croce, Irene Bozzoni
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Springer Nature 2020-06-01
Serie:	EMBO Molecular Medicine
Ämnen:	ATAC sequencing DMD Exon skipping iPSC Reprogramming lncRNAs trans‐generational epigenetic inheritance
Länkar:	https://doi.org/10.15252/emmm.202012063
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