Insulin growth factor 1 receptor expression is associated with NOTCH1 mutation, trisomy 12 and aggressive clinical course in chronic lymphocytic leukaemia.

IGF1R is emerging as an important gene in the pathogenesis of many solid and haematological cancers and its over-expression has been reported as frequently associated with aggressive disease and chemotherapy resistance. In this study we performed an investigation of the role of IGF1R expression in a...

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Principais autores:	Francesco Maura, Laura Mosca, Sonia Fabris, Giovanna Cutrona, Serena Matis, Marta Lionetti, Luca Agnelli, Marzia Barbieri, Marianna D'Anca, Martina Manzoni, Monica Colombo, Carlotta Massucco, Daniele Reverberi, Massimo Gentile, Anna Grazia Recchia, Sabrina Bossio, Fiorella Ilariucci, Caterina Musolino, Francesco Di Raimondo, Agostino Cortelezzi, Fortunato Morabito, Manlio Ferrarini, Antonino Neri
Formato:	Artigo
Idioma:	Inglês
Publicado:	Public Library of Science (PLoS) 2015-01-01
Series:	PLoS ONE
Acceso en liña:	http://europepmc.org/articles/PMC4365018?pdf=render
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