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Switch to tenecteplase for intravenous thrombolysis in stroke patients: experience from a German high-volume stroke center

Abstract Background Tenecteplase (TNK) offers promising efficacy and safety data for intravenous thrombolysis (IVT) in acute ischemic stroke (AIS) and pharmacological advantages over alteplase (rt-PA), justifying its gradual adoption as primary thrombolytic agent. At our tertiary care center, we tra...

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Hlavní autoři: Alexander Sekita, Gabriela Siedler, Jochen A. Sembill, Manuel Schmidt, Ludwig Singer, Bernd Kallmuenzer, Lena Mers, Anna Bogdanova, Stefan Schwab, Stefan T. Gerner
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2025-05-01
Edice:Neurological Research and Practice
Témata:
Ischemic stroke
Intravenous thrombolysis
Tenecteplase
Alteplase
Procedure times
Delayed time window
On-line přístup:https://doi.org/10.1186/s42466-025-00388-x
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