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Deep computational image analysis of immune cell niches reveals treatment-specific outcome associations in lung cancer

Abstract The tumor immune composition influences prognosis and treatment sensitivity in lung cancer. The presence of effective adaptive immune responses is associated with increased clinical benefit after immune checkpoint blockers. Conversely, immunotherapy resistance can occur as a consequence of...

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Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Cristian Barrera, Germán Corredor, Vidya Sankar Viswanathan, Ruiwen Ding, Paula Toro, Pingfu Fu, Christina Buzzy, Cheng Lu, Priya Velu, Philipp Zens, Sabina Berezowska, Merzu Belete, David Balli, Han Chang, Vipul Baxi, Konstantinos Syrigos, David L. Rimm, Vamsidhar Velcheti, Kurt Schalper, Eduardo Romero, Anant Madabhushi
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Nature Portfolio 2023-06-01
Цуврал:npj Precision Oncology
Онлайн хандалт:https://doi.org/10.1038/s41698-023-00403-x
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