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Ginsenoside Rg3 inhibits melanoma cell proliferation through down-regulation of histone deacetylase 3 (HDAC3) and increase of p53 acetylation.

Malignant melanoma is an aggressive and deadly form of skin cancer, and despite recent advances in available therapies, is still lacking in completely effective treatments. Rg3, a monomer extracted from ginseng roots, has been attempted for the treatment of many cancers. It is reported that the expr...

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Opis bibliograficzny
Główni autorzy: Xiu Shan, Yuan-Shan Fu, Faisal Aziz, Xiao-Qi Wang, Qiu Yan, Ji-Wei Liu
Format: Artigo
Język:Inglês
Wydane: Public Library of Science (PLoS) 2014-01-01
Seria:PLoS ONE
Dostęp online:https://doi.org/10.1371/journal.pone.0115401
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