Optimization of Resveratrol Used as a Scaffold to Design Histone Deacetylase (HDAC-1 and HDAC-2) Inhibitors

Histone deacetylases (HDAC) are epigenetic enzymes responsible for repressing gene expression through the deacetylation of histone lysine residues. Therefore, inhibition of HDACs has become an interesting approach for the treatment of several diseases, including cancer, hematology, neurodegenerative...

Szczegółowa specyfikacja

Opis bibliograficzny

Główni autorzy:	Beatriz Silva Urias, Aline Renata Pavan, Gabriela Ribeiro Albuquerque, Igor Muccilo Prokopczyk, Tânia Mara Ferreira Alves, Thais Regina Ferreira de Melo, Geraldo Rodrigues Sartori, João Hermínio Martins da Silva, Chung Man Chin, Jean Leandro Dos Santos
Format:	Artigo
Język:	Inglês
Wydane:	MDPI AG 2022-10-01
Seria:	Pharmaceuticals
Hasła przedmiotowe:	histone deacetylase resveratrol enzymatic inhibition gene regulation new drugs
Dostęp online:	https://www.mdpi.com/1424-8247/15/10/1260
Etykiety:	Dodaj etykietę Nie ma etykietki, Dołącz pierwszą etykiete!