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Substrate specificity of the ileal and the hepatic Na+/bile acid cotransporters of the rabbit. II. A reliable 3D QSAR pharmacophore model for the ileal Na+/bile acid cotransporter

To design a reliable 3D QSAR model of the intestinal Na+/bile acid cotransporter, we have used a training set of 17 inhibitors of the rabbit ileal Na+/bile acid cotransporter. The IC50 values of the training set of compounds covered a range of four orders of magnitude for inhibition of [3H]cholyltau...

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Bibliográfalaš dieđut
Váldodahkkit: Karl-Heinz Baringhaus, Hans Matter, Siegfried Stengelin, Werner Kramer
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Elsevier 1999-12-01
Ráidu:Journal of Lipid Research
Fáttát:
Liŋkkat:http://www.sciencedirect.com/science/article/pii/S0022227520320903
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